Treatment of periimplantitis with an enamel matrix protein derivative
T.M. AUSCHILL1, P. WINDISCH2, F. DÖRI2, and A. SCULEAN3,
1 Albert-Ludwigs-University Freiburg, Germany, 2 Semmelweis University, Budapest, Hungary, 3 University of Saarland, Homburg, Germany
The topical application of an enamel matrix protein derivative (EMD) onto periodontally compromised root surfaces has been shown to promote periodontal wound healing and regeneration. However, up to now no data are available on the healing of periimplantitis defects following treatment with EMD.
Objectives: To evaluate the effectiveness of EMD in the surgical treatment of periimplantitis.
Methods: A total of eight patients with one periimplantitis defect each were enrolled into the study. Following the elevation of full thickness mucoperiosteal flaps and careful removal of granulation tissue the implant surfaces were conditioned for 3 min. with a 24% EDTA gel. After rinsing with sterile saline in order to remove the EDTA residues EMD (Emdogain®, BIORA AB, Malmö, Sweden) was applied onto the implant surfaces and into the defects.
Results: At one year after surgery mean probing depth (PD) was reduced from 7.1 ± 1.5 mm to 3.5 ± 1.6 mm (p<0.001)>Conclusion: The present preliminary data suggest that the use of EMD after surgical treatment of periimplantitis leads to significant PD reduction, CAL gain and radiographic bone fill. Controlled histological and clinical studies are needed in order to further elucidate the relevance of this therapy for the treatment of periimplantitis.
1 Albert-Ludwigs-University Freiburg, Germany, 2 Semmelweis University, Budapest, Hungary, 3 University of Saarland, Homburg, Germany
The topical application of an enamel matrix protein derivative (EMD) onto periodontally compromised root surfaces has been shown to promote periodontal wound healing and regeneration. However, up to now no data are available on the healing of periimplantitis defects following treatment with EMD.
Objectives: To evaluate the effectiveness of EMD in the surgical treatment of periimplantitis.
Methods: A total of eight patients with one periimplantitis defect each were enrolled into the study. Following the elevation of full thickness mucoperiosteal flaps and careful removal of granulation tissue the implant surfaces were conditioned for 3 min. with a 24% EDTA gel. After rinsing with sterile saline in order to remove the EDTA residues EMD (Emdogain®, BIORA AB, Malmö, Sweden) was applied onto the implant surfaces and into the defects.
Results: At one year after surgery mean probing depth (PD) was reduced from 7.1 ± 1.5 mm to 3.5 ± 1.6 mm (p<0.001)>Conclusion: The present preliminary data suggest that the use of EMD after surgical treatment of periimplantitis leads to significant PD reduction, CAL gain and radiographic bone fill. Controlled histological and clinical studies are needed in order to further elucidate the relevance of this therapy for the treatment of periimplantitis.
posted by Ajou Huang | 9:29 AM
0 Comments:
Post a Comment
<< Home